Antigen Information

General Information of This Antigen
Antigen ID
TAR0LWLGS
Antigen Name
Kidney-associated antigen 1 (KAAG1)
Gene Name
KAAG1
Synonym
RU2AS; RU2 antisense gene protein
Sequence
MDDDAAPRVEGVPVAVHKHALHDGLRQVAGPGAAAAHLPRWPPPQLAASRREAPPLSQRP
HRTQGAGSPPETNEKLTNPQVKEK

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Uniprot Entry
KAAG1_HUMAN
HGNC ID
HGNC:21031
Each Antibody-drug Conjuate AND It's Component Related to This Antigen
Full List of The ADC Related to This Antigen
Anti-KAAG1 mAb
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
ADCT-901
SG3199
Human Deoxyribonucleic acid (hDNA)
Undisclosed
 [1]
Anti-KAAG1 mAb AB-3A4
 Antibody Info 
ADC Info ADC Name Payload Target Linker Ref
 ADC Info 
AB-3A4-Val-Cit-MMAE
Monomethyl auristatin E
Microtubule (MT)
Mc-Val-Cit-PABC
 [2]
References
Ref 1 First-in-human, phase 1, open-label, dose-escalation, dose-expansion study of ADCT-901 as monotherapy in patients with select advanced solid tumors. Journal of Clinical Oncology 2022 40:16_suppl, TPS3157-TPS3157.
Ref 2 AB-3A4: A novel KAAG1-targeting antibody-drug conjugate is active in models of ovarian carcinoma, triple-negative breast cancer and castration-resistant prostate cancer. Cancer Res (2014) 74 (19_Supplement): 666.

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