Antigen Information

General Information of This Antigen

Antigen ID	TAR0DPWRE
Antigen Name	Leukocyte antigen CD37 (CD37)
Gene Name	CD37
Synonym	TSPAN26; Tetraspanin-26;CD_antigen=CD37
Sequence	MSAQESCLSLIKYFLFVFNLFFFVLGSLIFCFGIWILIDKTSFVSFVGLAFVPLQIWSKV LAISGIFTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLR DVVEKTIQKYGTNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCS CYNLSATNDSTILDKVILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLHN NLISIVGICLGVGLLELGFMTLSIFLCRNLDHVYNRLARYR Click to Show/Hide
Family	Syndecan proteoglycan family
Uniprot Entry	CD37_HUMAN
HGNC ID	HGNC:1666
KEGG ID	hsa:951

Each Antibody-drug Conjuate AND It's Component Related to This Antigen

Full List of The ADC Related to This Antigen

AGS67C

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	AGS67E	MMAE	Microtubule (MT)	Mc-Val-Cit-PABC

Anti-CD37 antibody

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	HDP-102	Amanitin	RNA polymerase II	Undisclosed	[1]

Anti-CD37 mAb

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	dS3790a	DXd	DNA topoisomerase 1 (TOP1)	Mc-Gly-Gly-Phe-Gly

hmAb-H11a

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	hmAb-H11aL11-DXd	Undisclosed	Undisclosed	Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)	[2]

hmAb-H541

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	hmAb-H541L11-DXd	Undisclosed	Undisclosed	Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)	[2]

hmAb-H551

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	hmAb-H551L11-DXd	Undisclosed	Undisclosed	Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)	[2]

hmAb-L11

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	hmAbH11L11-Dxd	Undisclosed	Undisclosed	Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)	[2]

Naratuximab

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	Naratuximab emtansine	DM1	Microtubule (MT)	Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
ADC Info	iMGN529	Mertansine DM1	Undisclosed	Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)	[2]
ADC Info	debio 1562M	DM1	Microtubule (MT)	Multilink? Cleavable Linker

Undisclosed

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	NNV-014	Undisclosed	Undisclosed	Undisclosed	[3]
ADC Info	JAB-X1800	STING agonist	Stimulator of interferon genes protein (STING1)	Undisclosed	[4]
ADC Info	NNV-019	Undisclosed	Undisclosed	Undisclosed	[5]

References

Ref 1	Introduction to basic information on ADC drug by Heidelberg-pharma.
Ref 2	Anti-CD37 antibody-drug conjugate
Ref 3	Nordic Nanovector biotechnology company product pipeline
Ref 4	A JAB-X1800/JAB-BX400 introduction by Jacobio Pharmaceuticals.
Ref 5	ADC review LCB14-15XX (NNV019)