Antigen Information
General Information of This Antigen (ID: TAR0CHCZT)
| Antigen Name | Zinc transporter ZIP6 (SLC39A6) |
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| Gene Name | SLC39A6 |
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| Gene ID | ||||||
| Synonym | LIV1; ZIP6; Estrogen-regulated protein LIV-1;Solute carrier family 39 member 6;Zrt- and Irt-like protein 6 |
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| Sequence |
MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAISTRQYHLQQL
FYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSEH EHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKD SVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKT NESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDA RSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSF LVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDS TWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTN EEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKC HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVI MGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLY NALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCS RWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF Click to Show/Hide
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| Family | ZIP transporter family |
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| Function |
May act as a zinc-influx transporter.
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| Uniprot Entry | ||||||
| HGNC ID | ||||||
| KEGG ID | ||||||
Each Antibody-drug Conjugate and Its Component Related to This Antigen
Full List of The ADC Related to This Antigen
| The Numbers of ADCs, Their Three Components, Payload Targets, and Corresponding Diseases for This Antigens | ||||
|---|---|---|---|---|
Anti-LIV-1 mAb
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
SHR-7631
|
SHR9265 |
DNA topoisomerase 1 (TOP1) |
Undisclosed |
Ladiratuzumab
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
Ladiratuzumab vedotin
|
Monomethyl auristatin E |
Microtubule (MT) |
Mc-Val-Cit-PABC |
Laventatug
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
laventatug tivedotin
|
Monomethyl auristatin E |
Microtubule (MT) |
BrAc-Val-Cit-PABC |
Undisclosed
| ADC Name | Payload | Target | Linker | ADC Info |
|---|---|---|---|---|
|
BRY-812
|
Monomethyl auristatin E |
Microtubule (MT) |
Undisclosed |
|
|
HLX-41
[1]
|
Undisclosed |
Undisclosed |
Undisclosed |
|
|
BSI-712
[2]
|
Undisclosed |
Undisclosed |
Undisclosed |
References