Antigen Information

General Information of This Antigen

Antigen ID	TAR0CHCZT
Antigen Name	Zinc transporter ZIP6 (SLC39A6)
Gene Name	SLC39A6
Synonym	LIV1; ZIP6; Estrogen-regulated protein LIV-1;Solute carrier family 39 member 6;Zrt- and Irt-like protein 6
Sequence	MARKLSVILILTFALSVTNPLHELKAAAFPQTTEKISPNWESGINVDLAISTRQYHLQQL FYRYGENNSLSVEGFRKLLQNIGIDKIKRIHIHHDHDHHSDHEHHSDHERHSDHEHHSEH EHHSDHDHHSHHNHAASGKNKRKALCPDHDSDSSGKDPRNSQGKGAHRPEHASGRRNVKD SVSASEVTSTVYNTVSEGTHFLETIETPRPGKLFPKDVSSSTPPSVTSKSRVSRLAGRKT NESVSEPRKGFMYSRNTNENPQECFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDA RSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLMNRVFFKFLLSF LVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDS TWKGLTALGGLYFMFLVEHVLTLIKQFKDKKKKNQKKPENDDDVEIKKQLSKYESQLSTN EEKVDTDDRTEGYLRADSQEPSHFDSQQPAVLEEEEVMIAHAHPQEVYNEYVPRGCKNKC HSHFHDTLGQSDDLIHHHHDYHHILHHHHHQNHHPHSHSQRYSREELKDAGVATLAWMVI MGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTVKQAVLY NALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDASDHGCS RWGYFFLQNAGMLLGFGIMLLISIFEHKIVFRINF Click to Show/Hide
Family	ZIP transporter family
Function	May act as a zinc-influx transporter. Click to Show/Hide
Uniprot Entry	S39A6_HUMAN
HGNC ID	HGNC:18607
KEGG ID	hsa:25800

Each Antibody-drug Conjuate AND It's Component Related to This Antigen

Full List of The ADC Related to This Antigen

Anti-LIV-1 mAb

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	sHR-7631	SHR9265	DNA topoisomerase 1 (TOP1)	Undisclosed

Ladiratuzumab

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	Ladiratuzumab vedotin	MMAE	Microtubule (MT)	Mc-Val-Cit-PABC

Laventatug

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	laventatug tivedotin	MMAE	Microtubule (MT)	BrAc-Val-Cit-PABC

Undisclosed

Antibody Info

ADC Info	ADC Name	Payload	Target	Linker	Ref
ADC Info	BRY-812	Monomethyl auristatin E	Undisclosed	Undisclosed
ADC Info	HLX-41	Undisclosed	Undisclosed	Undisclosed	[1]
ADC Info	BSI-712	Undisclosed	Undisclosed	Undisclosed	[2]

References

Ref 1	Introduction to basic information on ADC drug HLX-41.
Ref 2	Biosion biotechnology company product pipeline