General Information of This Payload
Payload ID
PAY0XSTPE
Name
U-033
Synonyms
U-033
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Target DNA topoisomerase I (TOP1)
Formula
C26H26F3N3O7P
Isosmiles
O=C(OCC1=C2C=C3N(C1=O)CC4=C3N=C5C6=C4[C@@H](NC(C(F)F)=O)CCC6=C(C)C(F)=C5)[C@@]2(CC)OP(O)(O)=O
PubChem CID
US20250025571A1
Pharmaceutical Properties
Molecule Weight
552.46
Polar area
131.2
Complexity
760
xlogp Value
3.6
Heavy Count
39
Rot Bonds
8
Hbond acc
9
Hbond Donor
2
Each Antibody-drug Conjugate Related to This Payload