Payload Information

General Information of This Payload (ID: PAY0XJNEL)
Name
DT390
Synonyms
DT390
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Target Eukaryotic elongation factor 2 kinase (EEF2K)
 Target Info 
The activity data of This Payload
Standard Type Value Units Cell line Disease Model Cell line ID Reference
Survival Rate 43 % (Day60)
C57BL/6 enriched lymph node T cells
Normal
Undisclosed [1]
Survival Rate 43 % (Day80)
C57BL/6 enriched lymph node T cells
Normal
Undisclosed [1]
Survival Rate 57 % (Day40)
C57BL/6 enriched lymph node T cells
Normal
Undisclosed [1]
Each Antibody-drug Conjugate Related to This Payload
References
Ref 1 Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor. Blood. 1996 Sep 15;88(6):2342-53.