Payload Information

General Information of This Payload

Payload ID	PAY0XJNEL
Name	DT390
Synonyms	DT390 Click to Show/Hide
Target(s)	Eukaryotic elongation factor 2 (EEF2)	Target Info

The activity data of This Payload

Standard Type	Value	Units	Cell line	Disease Model	Cell line ID	Reference
Survival Rate	43	% (Day60)	C57BL/6 enriched lymph node T cells	Normal	Undisclosed	[1]
Survival Rate	43	% (Day80)	C57BL/6 enriched lymph node T cells	Normal	Undisclosed	[1]
Survival Rate	57	% (Day40)	C57BL/6 enriched lymph node T cells	Normal	Undisclosed	[1]

Each Antibody-drug Conjugate Related to This Payload

References

Ref 1	Anti-graft-versus-host disease effect of DT390-anti-CD3sFv, a single-chain Fv fusion immunotoxin specifically targeting the CD3 epsilon moiety of the T-cell receptor. Blood. 1996 Sep 15;88(6):2342-53.

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