General Information of This Payload
Payload ID
PAY0VOJYJ
Name
Cisplatin
Synonyms
Cisplatin; 14913-33-8; trans-Dichlorodiamineplatinum(II); azane;dichloroplatinum; Platinum, diamminedichloro-, (SP-4-1)-; trans-Diamminedichloro platinum(II); trans-Platinum(II)diammine dichloride; MFCD00011623; trans-Dichlorodiamineplatinum(II);Transplatin; SR-05000001586; IA call; Trans-Platinum diammine dichloride; Cisplatin in water; Cisplatin,(S); Cisplatin in DMSO; DDP-H; PLATINOL (TN); Cl2-H6-N2-Pt; [Pt](Cl)(Cl)(N)N; SPECTRUM1502107; Cisplatin (JP17/USP/INN); cis-Diaminodichloroplatinum(II); HMS502M12; HMS1921J18; HMS2092D04; BCP01792; BCP18182; CCG-39901; AKOS005137969; NCGC00094962-01; NCGC00094962-02; NCGC00094962-03; FT-0777996; C06911; D00275; cis-Diammineplatinum(II) dichloride, crystalline; Q412415; SR-01000076254; SR-01000076254-1; SR-05000001586-1; SR-05000001586-3; Z3182781436; Cisplatin, European Pharmacopoeia (EP) Reference Standard; Cisplatin, United States Pharmacopeia (USP) Reference Standard; cis-Diamineplatinum(II) dichloride, >=99.9% trace metals basis; Cisplatin impurity A, European Pharmacopoeia (EP) Reference Standard; Transplatin, United States Pharmacopeia (USP) Reference Standard; Cisplatin, Pharmaceutical Secondary Standard; Certified Reference Material
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Target(s) Human Deoxyribonucleic acid (hDNA)
Structure
Formula
Cl2H6N2Pt
Isosmiles
N.N.Cl[Pt]Cl
PubChem CID
5702198
InChI
InChI=1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
InChIKey
LXZZYRPGZAFOLE-UHFFFAOYSA-L
IUPAC Name
azane;dichloroplatinum
Pharmaceutical Properties
Molecule Weight
300.05
Polar area
2
Complexity
2.8
xlogp Value
.
Heavy Count
5
Rot Bonds
0
Hbond acc
2
Hbond Donor
2
The activity data of This Payload
Standard Type Value Units Cell line Disease Model Cell line ID Reference
Half Maximal Inhibitory Concentration (IC50) 48.49 nM
UACC-257 cells
Melanoma
CVCL_1779 
Each Antibody-drug Conjugate Related to This Payload

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