Payload Information
General Information of This Payload
| Payload ID | PAY0SAJTR |
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|---|---|---|---|---|---|---|
| Name | Topo1 inhibitor E |
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| Synonyms |
Topo1 inhibitor E
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C29H33FN4O5 |
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| Isosmiles | CN(C(CC1)CCN1CC(C2=CC(OC)=C(F)C=C2N=C3C4=CC([C@@]5(O)CC)=C6COC5=O)=C3CN4C6=O)C |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C29H33FN4O5/c1-5-29(37)21-11-24-26-19(14-34(24)27(35)20(21)15-39-28(29)36)18(13-33-8-6-16(7-9-33)32(2)3)17-10-25(38-4)22(30)12-23(17)31-26/h10-12,16,37H,5-9,13-15H2,1-4H3/t29-/m0/s1
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| InChIKey |
PMORWKKBBSSOCE-LJAQVGFWSA-N
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| Pharmaceutical Properties | Molecule Weight |
536.604 |
Polar area |
97.13 |
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Complexity |
1514.349321 |
xlogp Value |
2.7533 |
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Heavy Count |
39 |
Rot Bonds |
5 |
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Hbond acc |
9 |
Hbond Donor |
1 |
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Each Antibody-drug Conjugate Related to This Payload