Payload Information
General Information of This Payload
| Payload ID | PAY0QWHQJ |
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|---|---|---|---|---|---|---|
| Name | L078-043 payload |
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| Synonyms |
L078-043
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C28H27FN4O5 |
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| Isosmiles | CC[C@](C(C=C1C2=NC(C=C(F)C(C)=C3CC[C@H]4NC([C@@H]5CCN5)=O)=C3C4=C2CN1C6=O)=C6CO7)(O)C7=O |
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| InChI |
InChI=1S/C28H27FN4O5/c1-3-28(37)16-8-21-24-14(10-33(21)26(35)15(16)11-38-27(28)36)23-18(32-25(34)19-6-7-30-19)5-4-13-12(2)17(29)9-20(31-24)22(13)23/h8-9,18-19,30,37H,3-7,10-11H2,1-2H3,(H,32,34)/t18-,19+,28-/m1/s1
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| InChIKey |
HKEBNSIIBXANNR-FSQFJQELSA-N
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| Pharmaceutical Properties | Molecule Weight |
518.545 |
Polar area |
122.55 |
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Complexity |
1614.697235 |
xlogp Value |
1.99252 |
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Heavy Count |
38 |
Rot Bonds |
3 |
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Hbond acc |
8 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload