Payload Information
General Information of This Payload
| Payload ID | PAY0PMQSD |
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|---|---|---|---|---|---|---|
| Name | TLR7/8 agonist A |
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| Synonyms |
TLR7/8 agonist A
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| Target | Toll-like receptor 7 (TLR7); Toll-like receptor 8 (TLR8) | |||||
| Formula | C24H35N7O |
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| Isosmiles | CCCCCNC1=C2C(C=CN2CC3=CC=C(CN4CCNCC4)C=C3OC)=NC(N)=N1 |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C24H35N7O/c1-3-4-5-9-27-23-22-20(28-24(25)29-23)8-12-31(22)17-19-7-6-18(15-21(19)32-2)16-30-13-10-26-11-14-30/h6-8,12,15,26H,3-5,9-11,13-14,16-17H2,1-2H3,(H3,25,27,28,29)
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| InChIKey |
LMXTZUAHGZBEKB-UHFFFAOYSA-N
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| Pharmaceutical Properties | Molecule Weight |
437.592 |
Polar area |
93.26 |
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Complexity |
996.295372 |
xlogp Value |
3.0777 |
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Heavy Count |
32 |
Rot Bonds |
10 |
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Hbond acc |
8 |
Hbond Donor |
3 |
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The activity data of This Payload
| Standard Type | Value | Units | Cell line | Disease Model | Cell line ID | Reference |
|---|---|---|---|---|---|---|
| Half Maximal Effective Concentration (EC50) | <5 | nM | Undisclosed | Undisclosed | Undisclosed |
Each Antibody-drug Conjugate Related to This Payload