Payload Information
General Information of This Payload
| Payload ID | PAY0PHHQL |
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|---|---|---|---|---|---|---|
| Name | RU20241285-23-payload |
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| Synonyms |
RU20241285-23-payload
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C26H22F3N3O5 |
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| Isosmiles | CC[C@@](C(C=C1C2=NC(C=C(F)C(C)=C3CC[C@@H]4NC(C(F)F)=O)=C3C4=C2CN1C5=O)=C5CO6)(O)C6=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C26H22F3N3O5/c1-3-26(36)14-6-18-21-12(8-32(18)24(34)13(14)9-37-25(26)35)20-16(31-23(33)22(28)29)5-4-11-10(2)15(27)7-17(30-21)19(11)20/h6-7,16,22,36H,3-5,8-9H2,1-2H3,(H,31,33)/t16-,26-/m0/s1
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| InChIKey |
UNWXZOBEHFAQGJ-QMTYFTJSSA-N
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| Pharmaceutical Properties | Molecule Weight |
513.472 |
Polar area |
110.52 |
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Complexity |
1566.537054 |
xlogp Value |
2.89572 |
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Heavy Count |
37 |
Rot Bonds |
3 |
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Hbond acc |
7 |
Hbond Donor |
2 |
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Each Antibody-drug Conjugate Related to This Payload