Payload Information
General Information of This Payload
| Payload ID | PAY0PHBLD |
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|---|---|---|---|---|---|---|
| Name | Topo1 inhibitor G |
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| Synonyms |
Topo1 inhibitor G
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C30H34FN3O5 |
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| Isosmiles | CC(C(CC1)CCN1CC(C2=CC(OC)=C(F)C=C2N=C3C4=CC([C@@]5(O)CC)=C6COC5=O)=C3CN4C6=O)C |
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| InChI |
InChI=1S/C30H34FN3O5/c1-5-30(37)22-11-25-27-20(14-34(25)28(35)21(22)15-39-29(30)36)19(13-33-8-6-17(7-9-33)16(2)3)18-10-26(38-4)23(31)12-24(18)32-27/h10-12,16-17,37H,5-9,13-15H2,1-4H3/t30-/m0/s1
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| InChIKey |
GLCLQOMULUNFJA-PMERELPUSA-N
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| Pharmaceutical Properties | Molecule Weight |
535.616 |
Polar area |
93.89 |
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Complexity |
1514.349321 |
xlogp Value |
4.0953 |
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Heavy Count |
39 |
Rot Bonds |
5 |
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Hbond acc |
8 |
Hbond Donor |
1 |
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Each Antibody-drug Conjugate Related to This Payload