Payload Information
General Information of This Payload
| Payload ID | PAY0OXWAU |
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|---|---|---|---|---|---|---|
| Name | CN115160403A+B1+payload |
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| Synonyms |
CN115160403A+B1+payload
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C25H22FN3O6 |
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| Isosmiles | CC[C@]1(O)C(C=C2C3=NC4=CC(F)=C(NC(CO)=O)C(CCC5)=C4C5=C3CN62)=C(COC1=O)C6=O |
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| InChI |
InChI=1S/C25H22FN3O6/c1-2-25(34)15-6-18-22-13(8-29(18)23(32)14(15)10-35-24(25)33)11-4-3-5-12-20(11)17(27-22)7-16(26)21(12)28-19(31)9-30/h6-7,30,34H,2-5,8-10H2,1H3,(H,28,31)/t25-/m0/s1
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| InChIKey |
BMTWQVROQQNQAV-VWLOTQADSA-N
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| Pharmaceutical Properties | Molecule Weight |
479.464 |
Polar area |
130.75 |
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Complexity |
1501.996202 |
xlogp Value |
1.6382 |
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Heavy Count |
35 |
Rot Bonds |
3 |
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Hbond acc |
8 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload