Payload Information
General Information of This Payload
| Payload ID | PAY0OUSFB |
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|---|---|---|---|---|---|---|
| Name | CN112341521B+Payload11 |
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| Synonyms |
CN112341521B+Payload11
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C24H23N3O6S |
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| Isosmiles | O=S1(CCCN1CC2=C3C=CC=CC3=NC4=C2CN5C4=CC([C@@]6(O)CC)=C(COC6=O)C5=O)=O |
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| InChI |
InChI=1S/C24H23N3O6S/c1-2-24(30)18-10-20-21-16(12-27(20)22(28)17(18)13-33-23(24)29)15(11-26-8-5-9-34(26,31)32)14-6-3-4-7-19(14)25-21/h3-4,6-7,10,30H,2,5,8-9,11-13H2,1H3/t24-/m0/s1
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| InChIKey |
ADDJBLKSRJIUJU-DEOSSOPVSA-N
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| Pharmaceutical Properties | Molecule Weight |
481.53 |
Polar area |
118.8 |
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Complexity |
1518.482123 |
xlogp Value |
1.6151 |
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Heavy Count |
34 |
Rot Bonds |
3 |
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Hbond acc |
8 |
Hbond Donor |
1 |
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Each Antibody-drug Conjugate Related to This Payload