Payload Information
General Information of This Payload
| Payload ID | PAY0NAKHK |
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|---|---|---|---|---|---|---|
| Name | Topo1 inhibitor H |
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| Synonyms |
Topo1 inhibitor H
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C23H20N2O7 |
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| Isosmiles | CC[C@@](C(C=C1C2=C(C(CC)=C(C=C(O)C=C3)C3=N2)CN41)=C(C4=O)CO5)(OC(O)=O)C5=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C23H20N2O7/c1-3-12-13-7-11(26)5-6-17(13)24-19-14(12)9-25-18(19)8-16-15(20(25)27)10-31-21(28)23(16,4-2)32-22(29)30/h5-8,26H,3-4,9-10H2,1-2H3,(H,29,30)/t23-/m0/s1
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| InChIKey |
WNTZFHLPRSUOCW-QHCPKHFHSA-N
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| Pharmaceutical Properties | Molecule Weight |
436.42 |
Polar area |
127.95 |
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Complexity |
1357.274374 |
xlogp Value |
3.0499 |
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Heavy Count |
32 |
Rot Bonds |
3 |
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Hbond acc |
8 |
Hbond Donor |
2 |
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Each Antibody-drug Conjugate Related to This Payload