Payload Information
General Information of This Payload
| Payload ID | PAY0MPNDV |
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|---|---|---|---|---|---|---|
| Name | LT4212552T ADC10 payload |
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| Synonyms |
SCHEMBL16484793; SCHEMBL29540233
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C28H29FN4O5 |
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| Isosmiles | CC1=C(C2=C3C=C1F)CC[C@H](NC(CCCN)=O)C2=C(C(C4=CC([C@@]5(O)CC)=C6COC5=O)=N3)CN4C6=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C28H29FN4O5/c1-3-28(37)17-9-21-25-15(11-33(21)26(35)16(17)12-38-27(28)36)24-19(31-22(34)5-4-8-30)7-6-14-13(2)18(29)10-20(32-25)23(14)24/h9-10,19,37H,3-8,11-12,30H2,1-2H3,(H,31,34)/t19-,28-/m0/s1
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| InChIKey |
IIFWJWSJXZYUEK-VKGTZQKMSA-N
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| Pharmaceutical Properties | Molecule Weight |
520.561 |
Polar area |
136.54 |
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Complexity |
1568.537054 |
xlogp Value |
2.36952 |
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Heavy Count |
38 |
Rot Bonds |
5 |
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Hbond acc |
8 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload