Payload Information
General Information of This Payload
| Payload ID | PAY0LTEJZ |
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|---|---|---|---|---|---|---|
| Name | Topo1 inhibitor B |
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| Synonyms |
Topo1 inhibitor B
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C27H27FN4O6 |
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| Isosmiles | CC1=C(C2=C3C=C1F)CC[C@H](NC(OCCN)=O)C2=C(C(C4=CC([C@@]5(O)CC)=C6COC5=O)=N3)CN4C6=O |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C27H27FN4O6/c1-3-27(36)16-8-20-23-14(10-32(20)24(33)15(16)11-38-25(27)34)22-18(31-26(35)37-7-6-29)5-4-13-12(2)17(28)9-19(30-23)21(13)22/h8-9,18,36H,3-7,10-11,29H2,1-2H3,(H,31,35)/t18-,27-/m0/s1
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| InChIKey |
RVLSMCFRNMRFHD-MYUZEXMDSA-N
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| Pharmaceutical Properties | Molecule Weight |
522.533 |
Polar area |
145.77 |
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Complexity |
1568.537054 |
xlogp Value |
2.19932 |
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Heavy Count |
38 |
Rot Bonds |
4 |
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Hbond acc |
9 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload