Payload Information

General Information of This Payload

Payload ID	PAY0LHNVZ
Name	DNA topoisomerase-I inhibitor
Target(s)	DNA topoisomerase 1 (TOP1)	Target Info

Each Antibody-drug Conjugate Related to This Payload

Full Information of The Activity Data of The ADC(s) Related to This Payload

HS-20089 [Phase 3]

ADC Info

Identified from the Human Clinical Data

Click To Hide/Show 1 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC				[1]
*Related Clinical Trial*
NCT Number	NCT05263479	Phase Status	Phase 1
Clinical Description	A phase 1, open-label, multicenter study to evaluate safety, tolerability, pharmacokinetics, and efficacy of HS-20089 in patients with advanced solid tumors.

References

Ref 1	A Phase I, Open-label, Multicenter Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Efficacy of HS-20089 in Patients With Advanced Solid Tumors, NCT05263479