Payload Information
General Information of This Payload
| Payload ID | PAY0KWWSO |
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|---|---|---|---|---|---|---|
| Name | 4- ((S)-2- ((S)-2-amino-3-methylbutanamido)propanamido)benzyl ((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)carbamate |
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| Synonyms |
compound 32
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C40H43FN6O8 |
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| Isosmiles | C[C@H](NC([C@@H](N)C(C)C)=O)C(NC1=CC=C(COC(N[C@H]2CCC(C(C)=C(F)C=C3N=C4C5=CC([C@@]6(O)CC)=C7COC6=O)=C3C2=C4CN5C7=O)=O)C=C1)=O |
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| InChI |
InChI=1S/C40H43FN6O8/c1-6-40(53)26-13-30-34-24(15-47(30)37(50)25(26)17-54-38(40)51)32-28(12-11-23-19(4)27(41)14-29(45-34)31(23)32)46-39(52)55-16-21-7-9-22(10-8-21)44-35(48)20(5)43-36(49)33(42)18(2)3/h7-10,13-14,18,20,28,33,53H,6,11-12,15-17,42H2,1-5H3,(H,43,49)(H,44,48)(H,46,52)/t20-,28-,33-,40-/m0/s1
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| InChIKey |
ZACAMCPLQSLRJF-PICQSYHMSA-N
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| Pharmaceutical Properties | Molecule Weight |
754.816 |
Polar area |
203.97 |
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Complexity |
2275.829033 |
xlogp Value |
3.86732 |
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Heavy Count |
55 |
Rot Bonds |
9 |
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Hbond acc |
11 |
Hbond Donor |
5 |
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Each Antibody-drug Conjugate Related to This Payload