Payload Information

General Information of This Payload

Payload ID	PAY0JKSOV
Name	Gemcitabine and paclitaxel loaded liposome
Synonyms	Gemcitabine (GEM) and paclitaxel (PTX)-loaded liposome Click to Show/Hide
Target(s)	Human Deoxyribonucleic acid (hDNA)	Target Info

Each Antibody-drug Conjugate Related to This Payload

Full Information of The Activity Data of The ADC(s) Related to This Payload

AF-GPL [Investigative]

ADC Info

Revealed Based on the Cell Line Data

Click To Hide/Show 1 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC				[1]
Efficacy Data	Half Maximal Inhibitory Concentration (IC50)	0.45 ug/mL
Method Description	The cell viability of BxPC3 cells upon formulation treatment were evaluated by MTT assay.
In Vitro Model	Pancreatic ductal adenocarcinoma	BxPC-3 cells	CVCL_0186

References

Ref 1	Antibody fragment-conjugated gemcitabine and paclitaxel-based liposome for effective therapeutic efficacy in pancreatic cancer. Mater Sci Eng C Mater Biol Appl. 2018 Aug 1;89:328-335. doi: 10.1016/j.msec.2018.04.011. Epub 2018 Apr 11.

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