General Information of This Payload
Payload ID
PAY0JJJPM
Name
Topoisomerase I inhibitor
Synonyms
Topoisomerase I inhibitor
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Target(s) DNA topoisomerase 1 (TOP1)
Each Antibody-drug Conjugate Related to This Payload
Full Information of The Activity Data of The ADC(s) Related to This Payload
SKB-315 [Phase 1]
Identified from the Human Clinical Data
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Experiment 1 Reporting the Activity Date of This ADC [1]
Related Clinical Trial
NCT Number NCT05367635  Phase Status Phase 1
Clinical Description
A phase 1 clinical study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of SKB315 for injection in patients with advanced solid tumors expressing claudin 18.2.
References
Ref 1 A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of SKB315 for Injection in Patients With Advanced Solid Tumors Expressing Claudin18.2