Payload Information
General Information of This Payload
| Payload ID | PAY0DSPHQ |
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|---|---|---|---|---|---|---|
| Name | EP4494658A1 antibody-drug conjugate 1 payload |
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| Synonyms |
EP4494658A1 antibody-drug conjugate 1 payload
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C30H36N4O8 |
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| Isosmiles | CCC(C1=CC(OC(N(CCNC)CCOCCO)=O)=CC=C1N=C2C3=CC([C@@]4(O)CC)=C5COC4=O)=C2CN3C5=O |
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| InChI |
InChI=1S/C30H36N4O8/c1-4-19-20-14-18(42-29(38)33(9-8-31-3)10-12-40-13-11-35)6-7-24(20)32-26-21(19)16-34-25(26)15-23-22(27(34)36)17-41-28(37)30(23,39)5-2/h6-7,14-15,31,35,39H,4-5,8-13,16-17H2,1-3H3/t30-/m0/s1
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| InChIKey |
IOPJVUMCXZPUHP-PMERELPUSA-N
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| Pharmaceutical Properties | Molecule Weight |
580.638 |
Polar area |
152.45 |
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Complexity |
1538.727235 |
xlogp Value |
1.6711 |
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Heavy Count |
42 |
Rot Bonds |
11 |
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Hbond acc |
11 |
Hbond Donor |
3 |
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Each Antibody-drug Conjugate Related to This Payload