Payload Information
General Information of This Payload
| Payload ID | PAY0BMELK |
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|---|---|---|---|---|---|---|
| Name | TW202506738A-C-009-PAYLOAD |
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| Synonyms |
TW202506738A-C-009-PAYLOAD
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| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
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| Formula | C28H32N4O5 |
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| Isosmiles | CN(C1CCN(CC2=C3C=C4CN5C(C(COC6=O)=C([C@@]6(O)CC)C=C5C4=NC3=CC=C2O)=O)CC1)C |
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| PubChem CID | ||||||
| InChI |
InChI=1S/C28H32N4O5/c1-4-28(36)21-12-23-25-16(13-32(23)26(34)20(21)15-37-27(28)35)11-18-19(24(33)6-5-22(18)29-25)14-31-9-7-17(8-10-31)30(2)3/h5-6,11-12,17,33,36H,4,7-10,13-15H2,1-3H3/t28-/m0/s1
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| InChIKey |
PQRUGIUMNKEFEU-NDEPHWFRSA-N
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| Pharmaceutical Properties | Molecule Weight |
504.587 |
Polar area |
108.13 |
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Complexity |
1449.862213 |
xlogp Value |
2.3112 |
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Heavy Count |
37 |
Rot Bonds |
4 |
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Hbond acc |
9 |
Hbond Donor |
2 |
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Each Antibody-drug Conjugate Related to This Payload