Payload Information
General Information of This Payload
| Payload ID | PAY0AXTTO |
|||||
|---|---|---|---|---|---|---|
| Name | Topo1 inhibitor A |
|||||
| Synonyms |
Topo1 inhibitor A
Click to Show/Hide
|
|||||
| Target | DNA topoisomerase I (TOP1) | |||||
| Structure |
|
|||||
| Formula | C32H28FN3O6 |
|||||
| Isosmiles | CC1=C(C2=C3C=C1F)CC[C@H](NC(CC4=CC=CC(O)=C4)=O)C2=C(C(C5=CC([C@@]6(O)CC)=C7COC6=O)=N3)CN5C7=O |
|||||
| PubChem CID | ||||||
| InChI |
InChI=1S/C32H28FN3O6/c1-3-32(41)21-11-25-29-19(13-36(25)30(39)20(21)14-42-31(32)40)28-23(34-26(38)10-16-5-4-6-17(37)9-16)8-7-18-15(2)22(33)12-24(35-29)27(18)28/h4-6,9,11-12,23,37,41H,3,7-8,10,13-14H2,1-2H3,(H,34,38)/t23-,32-/m0/s1
|
|||||
| InChIKey |
ZTLJLPPMEGARRW-UDNBHOFDSA-N
|
|||||
| Pharmaceutical Properties | Molecule Weight |
569.589 |
Polar area |
130.75 |
||
Complexity |
1886.40185 |
xlogp Value |
3.57892 |
|||
Heavy Count |
42 |
Rot Bonds |
4 |
|||
Hbond acc |
8 |
Hbond Donor |
3 |
|||
Each Antibody-drug Conjugate Related to This Payload