Linker Information
General Information of This Linker (ID: LIN0KCWDR)
| Name |
Mal-PEG2Val-Cit-PAB-OH
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C29H42N6O9
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| Isosmiles |
CC(C)C(C(=O)N(C1=CC=C(C=C1)CO)C(CCCNC(=O)N)C(=O)N)NC(=O)CCOCCOCCN2C(=O)C=CC2=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C29H42N6O9/c1-19(2)26(33-23(37)11-14-43-16-17-44-15-13-34-24(38)9-10-25(34)39)28(41)35(21-7-5-20(18-36)6-8-21)22(27(30)40)4-3-12-32-29(31)42/h5-10,19,22,26,36H,3-4,11-18H2,1-2H3,(H2,30,40)(H,33,37)(H3,31,32,42)
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| InChIKey |
FUIUTNYVVFCDIA-UHFFFAOYSA-N
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| IUPAC Name |
5-(carbamoylamino)-2-[N-[2-[3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoylamino]-3-methylbutanoyl]-4-(hydroxymethyl)anilino]pentanamide
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| Pharmaceutical Properties |
Molecule Weight
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618.7
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Polar area
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224
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Complexity
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1010
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xlogp Value
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-1.6
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Heavy Count
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44
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Rot Bonds
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20
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Hbond acc
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9
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Hbond Donor
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5
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Each Antibody-drug Conjugate Related to This Linker