Linker Information
General Information of This Linker
| Linker ID |
LIN0AROFL
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-adipamide-Ala-Ala
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C18H26N4O7
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| Isosmiles |
CC(NC(=O)C(C)NC(=O)CCCCC(=O)NCCN1C(=O)C=CC1=O)C(=O)O
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| InChI |
InChI=1S/C18H26N4O7/c1-11(17(27)21-12(2)18(28)29)20-14(24)6-4-3-5-13(23)19-9-10-22-15(25)7-8-16(22)26/h7-8,11-12H,3-6,9-10H2,1-2H3,(H,19,23)(H,20,24)(H,21,27)(H,28,29)
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| InChIKey |
CPKFQVOFDMYIRV-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
410.427
|
Polar area
|
161.98
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Complexity
|
29
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xlogp Value
|
-1.318
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Heavy Count
|
29
|
Rot Bonds
|
12
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Hbond acc
|
6
|
Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker
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