Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0ZVBAM |
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|---|---|---|---|---|---|---|
| Antibody Name | Minibody (4 cys) |
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| Synonyms |
Minibody (4 cys)
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| Antigen Name | Receptor tyrosine-protein kinase erbB-2 (ERBB2) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
mb (4)-m- (b-PEG12)-VC-MMAE [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
0.022 nM
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High HER2 expression (HER2+++) | ||
| Method Description |
IC50 (in nM) cell-based assays of tested entities on breast cancer cell lines MDA-MB-231 (HER2-low)
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| In Vitro Model | Breast adenocarcinoma | MDA-MB-231 cells (HER2 low) | CVCL_0062 | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Effective Concentration (EC50) |
312.1 nM
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Low HER2 expression (HER2+) | ||
| Method Description |
IC50 (in nM) cell-based assays of tested entities on breast cancer cell lines MDA-MB-231 (HER2-low)
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| In Vitro Model | Breast adenocarcinoma | MDA-MB-231 cells (HER2 low) | CVCL_0062 | ||
References