Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0PPMOC |
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| Antibody Name | AB185 |
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| Synonyms |
AB185
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| Antigen Name | Receptor tyrosine-protein kinase erbB-2 (ERBB2) |
Antigen Info | ||||
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Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
EDB-diS-L19-4574 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
429 ng/mL
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Negative EDB expression (EDB-) | ||
| Method Description |
Calculated using four-parameter logistic model #203 with XLfit v4.8 (IDBS)
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| In Vitro Model | Colon cancer | HT29 cells | CVCL_A8EZ | ||
| Experiment 2 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
487 ng/mL
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Positive EDB expression (EDB+++/++) | ||
| Method Description |
Calculated using four-parameter logistic model #203 with XLfit v4.7 (IDBS)
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| In Vitro Model | Normal | WI38-VA13 cells | CVCL_2759 | ||