Cell cytotoxicity was monitored using a specific assay (Abcam, Cambridge, UK- Cat # 112118). This cytotoxicity assay is based on the measurement of mitochondrial dehydrogenase activity using a specific dye. This assay evaluates the metabolic activity of viable cells. Cells were plated at 1500 cells/well in 100 ul culture medium. The following day, 100 ul of increasing concentrations of mAb, diluted in culture medium, were added to each well. Cells were incubated for 96 h at 37 °C in a 5% CO2 incubator. The OD570/OD605 nm ratio was used to determine cell viability in each well in triplicate according to the instructions. Data were analyzed using Prism 9.4 (GraphPad Software San Diego, CA, USA) to determine the half maximal inhibitory concentration (IC50) using the variable slope model after checking that we had a normal distribution of these data by a D'Agostino & Pearson test.