Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0CTVJD |
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| Antibody Name | 8D9 |
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| Organization | XADCERA BIOPHARMACEUTICAL (SUZHOU) CO., LTD. |
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| Synonyms |
8D9
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| Antigen Name | Trophoblast glycoprotein (TPBG) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
| Heavy Chain CDR 1 |
GHYWS
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| Heavy Chain CDR 2 |
YITYSGSTNYNPSLKS
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| Heavy Chain CDR 3 |
IAVAGRVYYYGVDV
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| Light Chain CDR 1 |
RASQSVSSYLA
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| Light Chain CDR 2 |
DASNRAT
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| Light Chain CDR 3 |
QQRSNWPPT
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Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
WO2024193682A1 8D9-ADC [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) | > 100 ug/ml | |||
| Method Description |
Series diluted ADCs (maximum concentration: 20 ug/mL, 3-fold dilutions, 10 gradients)were used to treat human lung squamous carcinoma NCI-H226 5000cells cultured in a cellculture plate, and the killing activity was detected after 72 hours of incubation in IncuCyte (Sartorius AG, IncuCytee S3).
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| In Vitro Model | Pleural epithelioid mesothelioma | NCI-H226 cells | CVCL_1544 | ||