Antibody Information
General Information of This Antibody
| Antibody ID | ANTI0CFTWJ |
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| Antibody Name | 3H9 |
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| Synonyms |
3H9
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| Antigen Name | Prion-like protein doppel (PRND) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
uS20240091372A1 3H9-vc-MMAE [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
29.65 Nm
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| Method Description |
A cell line expressing doppel, HCT116, was selected and cultured with increasing concentrations of ADC. After 72 hours, viability of each culture was assessed. ICso values were calculated by logistic non-linear regression and reported as nM.
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| In Vitro Model | Colon carcinoma | HCT116 cells | CVCL_0291 | ||
uS20240091372A1 3H9-KGDEVD-MMAE [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal inhibitory Concentration (lC50) |
39.32 Nm
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| Method Description |
A cell line expressing doppel, HCT116, was selected and cultured with increasing concentrations of ADC. After 72 hours, viability of each culture was assessed. ICso values were calculated by logistic non-linear regression and reported as nM.
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| In Vitro Model | Colon carcinoma | HCT116 cells | CVCL_0291 | ||