Antibody Information
General Information of This Antibody
| Antibody ID | ANI0ZCCGG |
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| Antibody Name | Hu033-03 |
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| Synonyms |
Hu033-03
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| Antigen Name | C-type lectin domain family 4 member C (CLEC4C) |
Antigen Info | ||||
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Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
DB-2304 [Phase 1/2]
Identified from the Human Clinical Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Patients Enrolled |
Key inclusion for Part A: healthy volunteers aged 18-55; BMI-compliant; normal medical history/physical exams/lab tests/ECG; commitment to effective contraception and protocol compliance.
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| Related Clinical Trial | |||||
| NCT Number | NCT06625671 | Clinical Status | PHASE1 | ||
| Clinical Description |
A Randomized, Double-Blind, Placebo- and Positive-Controlled, Single Ascending Dose Phase 1 Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DB-2304 Injection in Healthy Adult Participants
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| Primary Endpoint |
Primary safety endpoints include TEAEs and SAEs (monitored up to 112 days for Part A/196 days for Part B post-treatment), ECG parameters (HR/PR/QT/QTcF intervals), and vital sign measurements (weight, heart rate, pulse, respiratory rate, body temperature) with baseline change analysis.
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