Antibody Information
General Information of This Antibody
| Antibody ID | ANI0YJTON |
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| Antibody Name | DP001 |
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| Antibody Type | Monoclonal antibody (mAb) |
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| Antibody Subtype | Humanized IgG1-kappa |
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| Antigen Name | Receptor tyrosine-protein kinase erbB-2 (ERBB2) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
| Heavy Chain Sequence |
EVQLVESGGGLVQPGGSLRLSCAASGFNIKDTYIHWVRQAPGKGLEWVARIYPTNGYTRY
ADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCSRWGGDGFYAMDYWGQGTLVTVSS Click to Show/Hide
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| Light Chain Sequence |
DIQMTQSPSSLSASVGDRVTITCRASQDVNTAVAWYQQKPGKAPKLLIYSASFLYSGVPS
RFSGSRSGTDFTLTISSLQPEDFATYYCQQHYTTPPTFGQGTKVEIK Click to Show/Hide
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The Activity Data of This Antibody
| Antibody Activity Information 1 | [1] | |||||
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Half Maximal Effective Concentration (EC50)
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4.1
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ng/mL
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| Antibody Function | Confirm the effect of the drug conjugation with the anti HER2 mAb and ADC on binding activity to cell line. | |||||
| Antibody Antigen Binding Assay | The DP303cs affinity for HER2 was determined by ELISA, cell-based assay, and BLI analysis. | |||||
| Antibody Activity Information 2 | [1] | |||||
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Half Maximal Effective Concentration (EC50)
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124.6
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ng/mL
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SK-BR-3 cells | CVCL_0033 | ||
| Antibody Function | Confirm the effect of the drug conjugation with the anti HER2 mAb and ADC on binding activity to cell line. | |||||
| Antibody Antigen Binding Assay | The DP303cs affinity for HER2 was determined by ELISA, cell-based assay, and BLI analysis. | |||||
Each Antibody-drug Conjugate Related to This Antibody
References