Antibody Information
General Information of This Antibody
| Antibody ID | ANI0YCMBJ |
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| Antibody Name | Anti-CD24 G7mAb |
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| Antibody Type | Anti-CD24 G7mAb |
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| Antibody Subtype | Humanized IgG1-kappa |
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| Antigen Name | Signal transducer CD24 (CD24) |
Antigen Info | ||||
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Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
HN-01 [Investigative]
Discovered Using Cell Line-derived Xenograft Model
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Tumor Growth Inhibition value (TGI) | ≈ 81.30% | Positive CD24 expression (CD24 +++/++) | ||
| Method Description |
A hepatocellular carcinoma xenograft model was established by subcutaneously injecting BEL-7402 cells (1 x 107) into right flanks of BALB/c nude mice. When the average tumor volume reached 100 mm3, tumor-bearing mice were divided randomly into seven groups (six mice/group) and treated with HN-01 (10 mg/kg) every 3 days.
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| In Vivo Model | BEL-7402 CDX model | ||||
| In Vitro Model | Hepatoma | Bel-7402 cells | CVCL_5492 | ||
References