Antibody Information

General Information of This Antibody

Antibody ID	ANI0TSTNV
Antibody Name	Glyco-engineered cetuximab Fc/Fab
Antibody Type	Monoclonal antibody (mAb)
Antibody Subtype	Chimeric IgG1-Fab/Fc
Antigen Name	Epidermal growth factor receptor (EGFR)	Antigen Info

Each Antibody-drug Conjugate Related to This Antibody

Full Information of The Activity Data of The ADC(s) Related to This Antibody

Cetux Fc/Fab-vc-MMAE [Investigative]

ADC Info

Revealed Based on the Cell Line Data

Click To Hide/Show 1 Activity Data Related to This Level

Experiment 1 Reporting the Activity Date of This ADC					[1]
Efficacy Data	Half Maximal Inhibitory Concentration (IC50)	0.03 nM	High EGFR expression (EGFR+++)
Method Description	The effect of MMAE-conjugated cetuximab ADCs on the viability of U87 glioblastoma cells that express EGFR.
In Vitro Model	Glioblastoma	U-87MG cells		CVCL_0022

References

Ref 1	MAbs. 2023 Jan-Dec;15(1):2149057. doi: 10.1080/19420862.2022.2149057.

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