Antibody Information
General Information of This Antibody
| Antibody ID | ANI0RDZPJ |
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| Antibody Name | Grisnilimab |
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| Organization | Xenikos BV |
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| Indication | Steroid-refractory acute GvHD (SR-GvHD) |
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| Synonyms |
WT1
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| Antibody Type | Monoclonal antibody (mAb) |
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| Antibody Subtype | Mus musculus IgG2a-lambda |
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| Antigen Name | T-cell antigen CD7 (CD7) |
Antigen Info | ||||
| Click to Show/Hide the Sequence Information of This Antibody | ||||||
| Heavy Chain Sequence |
QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLMWLGWINTYTGEPTY
ADDFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWAYFYGSSPYFFDYWGQGTTLT VSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVL QSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPTIKPCPPCKCPAPNL LGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQTHRE DYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPKGSVRAPQVYVLPPP EEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDSDGSYFMYSKLRVEK KNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK Click to Show/Hide
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| Heavy Chain Varible Domain |
QIQLVQSGPELKKPGETVKISCKASGYTFTNYGMNWVKQAPGKGLMWLGWINTYTGEPTY
ADDFKGRFAFSLETSASTAYLQINNLKNEDTATYFCARWAYFYGSSPYFFDYWGQGTTLT VSS Click to Show/Hide
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| Heavy Chain Constant Domain 1 |
AKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPAVLQSD
LYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKI Click to Show/Hide
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| Heavy Chain Constant Domain 2 |
APNLLGGPSVFIFPPKIKDVLMISLSPIVTCVVVDVSEDDPDVQISWFVNNVEVHTAQTQ
THREDYNSTLRVVSALPIQHQDWMSGKEFKCKVNNKDLPAPIERTISKPK Click to Show/Hide
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| Heavy Chain Constant Domain 3 |
GSVRAPQVYVLPPPEEEMTKKQVTLTCMVTDFMPEDIYVEWTNNGKTELNYKNTEPVLDS
DGSYFMYSKLRVEKKNWVERNSYSCSVVHEGLHNHHTTKSFSRTPGK Click to Show/Hide
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| Heavy Chain Hinge Region |
EPRGPTIKPCPPCKCP
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| Heavy Chain CDR 1 |
GYTFTNYG
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| Heavy Chain CDR 2 |
INTYTGEP
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| Heavy Chain CDR 3 |
ARWAYFYGSSPYFFDY
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| Light Chain Sequence |
QAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGV
PARFSGSLIGDKAALTITGAQTEDEAIYFCALWCSNHLVFGGGTKLTVLGQPKSSPSVTL FPPSSEELETNKATLVCTITDFYPGVVTVDWKVDGTPVTQGMETTQPSKQSNNKYMASSY LTLTARAWERHSSYSCQVTHEGHTVEKSLSRADCS Click to Show/Hide
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| Light Chain Varible Domain |
QAVVTQESALTTSPGETVTLTCRSSTGAVTTSNYANWVQEKPDHLFTGLIGGTNNRAPGV
PARFSGSLIGDKAALTITGAQTEDEAIYFCALWCSNHLVFGGGTKLTVL Click to Show/Hide
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| Light Chain Constant Domain |
GQPKSSPSVTLFPPSSEELETNKATLVCTITDFYPGVVTVDWKVDGTPVTQGMETTQPSK
QSNNKYMASSYLTLTARAWERHSSYSCQVTHEGHTVEKSLSRADCS Click to Show/Hide
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| Light Chain CDR 1 |
TGAVTTSNY
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| Light Chain CDR 2 |
GTN
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| Light Chain CDR 3 |
ALWCSNHLV
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Each Antibody-drug Conjugate Related to This Antibody
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