Antibody Information
General Information of This Antibody
| Antibody ID | ANI0ELIEV |
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|---|---|---|---|---|---|---|
| Antibody Name | c213B10 |
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| Antibody Type | Monoclonal antibody (mAb) |
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| Antibody Subtype | Chimeric IgG1-kappa |
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| Antigen Name | Insulin-like growth factor 1 receptor (IGF1R) |
Antigen Info | ||||
Each Antibody-drug Conjugate Related to This Antibody
Full Information of The Activity Data of The ADC(s) Related to This Antibody
c213B10-G-13 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Inhibitory Concentration (IC50) |
0.10 nM
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Positive IGF1R expression (IGF1R+++/++) | ||
| Method Description |
MCF-7 cells were incubated with increasing concentrations of each ADCs at 37°C for 6 days in complete culture medium.
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| In Vitro Model | Invasive breast carcinoma | MCF-7 cells | CVCL_0031 | ||
c213B10-F-13 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Inhibitory Concentration (IC50) |
0.10 nM
|
Positive IGF1R expression (IGF1R+++/++) | ||
| Method Description |
MCF-7 cells were incubated with increasing concentrations of each ADCs at 37°C for 6 days in complete culture medium.
|
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| In Vitro Model | Invasive breast carcinoma | MCF-7 cells | CVCL_0031 | ||
c213B10-F-63 [Investigative]
Revealed Based on the Cell Line Data
| Experiment 1 Reporting the Activity Date of This ADC | [1] | ||||
| Efficacy Data | Half Maximal Inhibitory Concentration (IC50) |
0.10 nM
|
Positive IGF1R expression (IGF1R+++/++) | ||
| Method Description |
MCF-7 cells were incubated with increasing concentrations of each ADCs at 37°C for 6 days in complete culture medium.
|
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| In Vitro Model | Invasive breast carcinoma | MCF-7 cells | CVCL_0031 | ||
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