General Information of This Antibody-drug Conjugate (ID: DRG0ZIFBH)
ADC Name
GenSci143
Synonyms
GenSci143
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Organization
GeneScience Pharmaceuticals (Originator)
Drug Status
Phase 1
Antibody Name
Anti-B7H3/PSMA bsAb
 Antibody Info 
Antigen Name
CD276 antigen; Glutamate carboxypeptidase 2 (FOLH1)
 Antigen Info 
Payload Name
GSC5181
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07252414; CTR20254507
Prostate cancer
1 Trials
Trial ID
NCT07252414; CTR20254507