Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0YYVGW
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
SKB571
|
|||||
| Synonyms |
SKB571; MK-2750
Click to Show/Hide
|
|||||
| Organization |
Kelun Biotherapeutics (Originator);Merck & Co. (Top20 MNC)
|
|||||
| Drug Status |
Phase 2
|
|||||
| Drug-to-Antibody Ratio |
6
|
|||||
| Antibody Name |
Anti-EGFR/c-Met bsAb
|
Antibody Info | ||||
| Antigen Name |
Hepatocyte growth factor receptor (MET); Epidermal growth factor receptor (EGFR)
|
Antigen Info | ||||
| Payload Name |
KL610348
|
Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase 1 (TOP1)
|
Target Info | ||||
| Linker Name |
Kthiol (pyrimidine-thiol) AAA linker
|
Linker Info | ||||
| Conjugate Type |
Undisclosed
|
|||||
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
| Indication | Phase 1 | Phase 1/2 | Phase 2 | Phase 2/3 | Phase 3 | New Drug Application | Approved | |||
|---|---|---|---|---|---|---|---|---|---|---|
| Lung cancer |
2 Trials
|
|||||||||
| Unspecific solid tumor |
1 Trials
|