General Information of This Antibody-drug Conjugate (ID: DRG0YYVGW)
ADC Name
SKB571
Synonyms
SKB571; MK-2750
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Organization
Kelun Biotherapeutics (Originator);Merck & Co. (Top20 MNC)
Drug Status
Phase 2
Drug-to-Antibody Ratio
6
Antibody Name
Anti-EGFR/c-Met bsAb
 Antibody Info 
Antigen Name
Hepatocyte growth factor receptor (MET); Epidermal growth factor receptor (EGFR)
 Antigen Info 
Payload Name
KL610348
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
Kthiol (pyrimidine-thiol) AAA linker
 Linker Info 
Conjugate Type
Undisclosed
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Disease Name Phase 1 Phase 2 Phase 3 Approved
Lung cancer
2 Trials
Clinical trial identifier
NCT07308106; CTR20255006
NCT07230405; CTR20254041
Unspecific solid tumor
1 Trials
Clinical trial identifier
NCT06725381; CTR20244432