General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0WMIKO
ADC Name
hMPL-A251
Synonyms
HMPL-A251
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Organization
HUTCHMED (Originator)
Drug Status
Phase 1/2
Drug-to-Antibody Ratio
4
Antibody Name
HMA000352
 Antibody Info 
Antigen Name
Receptor tyrosine-protein kinase erbB-2 (HER2 ECD2); Receptor tyrosine-protein kinase erbB-2 (HER2 ECD4)
 Antigen Info 
Payload Name
HM5041609
 Payload Info 
Therapeutic Target
PI3K; PIKK
 Target Info 
Linker Name
A cleavable linker
 Linker Info 
Conjugate Type
Undisclosed
The indication landscape of This ADC(2027 Update)
The clinical trial pipeline of This ADC(2027 Update)
Indication Phase 1 Phase 1/2 Phase 2 Phase 2/3 Phase 3 New Drug Application Approved
Unspecific solid tumor
1 Trials
Trial ID
NCT07228247; CTR20254667