General Information of This Antibody-drug Conjugate (ID: DRG0VZLQX)
ADC Name
BNT329
Synonyms
BNT329
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Organization
BioNTech (Originator)
Drug Status
Phase 1/2
Structure
Antibody Name
Anti-CA19-9 antibody
 Antibody Info 
Antigen Name
CA19-9
 Antigen Info 
Payload Name
YL0010014
 Payload Info 
Payload Target
DNA topoisomerase 1 (TOP1)
 Target Info 
Linker Name
VK*G-NHCH2-O linker
 Linker Info 
Conjugate Type
Random Cysteines
Combination Type
pelitecan
2027 Update
The disease landscape of This ADC
2027 Update
The clinical trial pipelines of This ADC
Indication Phase 1 Phase 2 Phase 3 Approved
Gastroesophageal junction adenocarcinoma
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Colorectal cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Pancreatic cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Biliary tract cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Ovarian cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Endometrial cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00
Urothelial cancer
1 Trials
Trial ID
NCT07186842; EudraCT2025-522613-26; EUCT2025-522613-26-00