Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0VZHPP
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| ADC Name |
38751786 5D3 (CC-MLB8237)3.2-CF750
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| Synonyms |
5D3 (CC-MLB8237)3.2-CF750 ADC
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| Organization |
The Johns Hopkins University School of Medicine; Johns Hopkins University; Institute of Biotechnology of the Czech Academy of Sciences; University Medical Center Utrecht.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
3.2
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| Structure |
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| Antibody Name |
5D3 mAb-CF750
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Antibody Info | ||||
| Antigen Name |
Glutamate carboxypeptidase 2 (FOLH1)
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Antigen Info | ||||
| Payload Name |
MLN8237
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Payload Info | ||||
| Therapeutic Target |
Aurora kinase A (AURKA)
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Target Info | ||||
| Linker Name |
NHS-PEG-TCO-Tz
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Linker Info | ||||
| Conjugate Type |
Random conjugation through nucleophilic lysines.
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