Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UUUVA
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| ADC Name |
Tmab-VcMMAE-SMCC-DM1
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| Synonyms |
Tmab-VcMMAE-SMCC-DM1
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| Organization |
The University of Sydney.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2.83; 5.25
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
Monomethyl auristatin E
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Payload Info | ||||
| Payload Name |
Maytansinoid DM1
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Payload Info | ||||
| Linker Name |
Mc-Val-Cit-PABC
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Linker Info | ||||
| Linker Name |
Succinimidyl-4- (N-maleimidomethyl)cyclohexane-1-carboxylate (SMCC)
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Linker Info | ||||