Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UOAJM
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| ADC Name |
Anti-GPC2 ADC
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| Synonyms |
Anti GPC2 ADC
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| Organization |
The Children's Hospital of Philadelphia
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| Drug Status |
Clinical candidate
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| Antibody Name |
Undisclosed
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| Antigen Name |
Glypican-2 (GPC2)
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Antigen Info | ||||
| Payload Name |
Undisclosed
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| Therapeutic Target |
Stimulator of interferon genes protein (STING1)
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Target Info | ||||
| Linker Name |
Undisclosed
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| Conjugate Type |
Y289L mutant beta4Gal-T1 enzyme was used to conjugate GalNaz to terminal biantennary N-acetylglucosamines followed by click-reaction conjugation of a DBCO-activated PBD-payload.
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