Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0UEKUC
|
|||||
|---|---|---|---|---|---|---|
| ADC Name |
nHC-C-VA-Compound140
|
|||||
| Synonyms |
NHC-C-VA-Compound140
Click to Show/Hide
|
|||||
| Organization |
ZYMEWORKS BC INC.
|
|||||
| Drug Status |
Investigative
|
|||||
| Structure |
|
|||||
| Antibody Name |
Undisclosed
|
Antigen Name |
Undisclosed
|
|||
| Payload Name |
10NH2-11F-Camptothecin
|
Payload Info | ||||
| Therapeutic Target |
DNA topoisomerase I (TOP1)
|
Target Info | ||||
| Linker Name |
TW202426058A+NHC-C--VA-Compound140+Linker
|
Linker Info | ||||
| Conjugate Type |
Random conjugation through reduced inter-chain cysteines
|
|||||