Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0QDEAI
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| ADC Name |
Trastuzumab-NGM-PROTAC conjugate
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| Synonyms |
Trastuzumab NGM PROTAC conjugate; Ab-PROTAC 3
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| Drug Status |
Investigative
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| Indication |
In total 1 Indication(s)
Breast cancer [ICD11:2C60-2C65]
Investigative
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| Drug-to-Antibody Ratio |
4
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
BRD4 PROTAC 3
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Payload Info | ||||
| Therapeutic Target |
Bromodomain-containing protein 4 (BRD4)
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Target Info | ||||
| Linker Name |
NGM based linker
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Linker Info | ||||
| Conjugate Type |
Inter-chain cysteine.
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