Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0PSWOG
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| ADC Name |
T-PBA
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| Synonyms |
T-PBA
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| Organization |
Sichuan University
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2.26
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| Structure |
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| Antibody Name |
Trastuzumab
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
PBD-based payload 37b3
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Payload Info | ||||
| Therapeutic Target |
Human Deoxyribonucleic acid (hDNA)
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Target Info | ||||
| Linker Name |
MC-Val-Ala-OH linker
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Linker Info | ||||
| Conjugate Type |
Cysteine-maleimide conjugation
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| Combination Type |
Drug-linker 21
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