Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0OWPAR
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| ADC Name |
Anti-CD70 ADC 8-5
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| Synonyms |
Anti-CD70-ADC-8-5
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| Organization |
Merck & Co., Inc.
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
2
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| Structure |
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| Antibody Name |
Anti-CD70 mAb 2H5
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Antibody Info | ||||
| Antigen Name |
CD70 antigen (CD70)
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Antigen Info | ||||
| Payload Name |
Undisclosed
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| Therapeutic Target |
Stimulator of interferon genes protein (STING1)
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Target Info | ||||
| Linker Name |
Anti-CD70 ADC 8-5 linker
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| Conjugate Type |
The drug linker was conjugated to the unnatural amino acid (UAA) para-azido phenylalanine (p-AF)
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