General Information of This Antibody-drug Conjugate (ADC)
ADC ID
DRG0OQXQI
ADC Name
P2-528mAb
Synonyms
P2-528mAb
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Organization
Commonwealth Scientific and Industrial Research Organization; University of Queensland.
Drug Status
Investigative
Drug-to-Antibody Ratio
1
Structure
Antibody Name
528mAb
 Antibody Info 
Antigen Name
Epidermal growth factor receptor (EGFR)
 Antigen Info 
Payload Name
Undisclosed
Therapeutic Target
Stimulator of interferon genes protein (STING1)
 Target Info 
Linker Name
Undisclosed
Conjugate Type
Random conjugation through nucleophilic lysines.
ADC-specific functional property(2027 Update)
Binding Affinity
Click To Hide/Show 1 ADC-specific functional property Data
Dissocation Constant (Kd) Binding Target Description Reference
3.0±0.1 nM
EGFR
Surface plasmon resonance (SPR)
[1]
References
Ref 1 RAFT Polymer-Antibody Conjugation: Squaramide Ester Chemistry Leads to Conjugates with a Therapeutic Anti-EGFR Antibody with Full Retention of Activity and Increased Tumor Uptake In Vivo