General Information of This Antibody-drug Conjugate (ID: DRG0NZTGT)
ADC Name
LBL-054
Synonyms
LBL-054
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Organization
Nanjing Leadsbiolabs Co., Ltd.
Drug Status
Investigative
Antibody Name
humanized CDH17 IgG1 monoclonal antibody
 Antibody Info 
Antigen Name
Cadherin-17 (CDH17)
 Antigen Info 
Payload Name
Undisclosed
Linker Name
Undisclosed
2027 Update
ADC-specific functional property
Bystander Killing Effect
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Bystander Killing Effect Description Reference
yes
LBL-054 exhibited stronger bystander effect than LBL-054-Dxd conjugate.
[1]
References
Ref 1 Novel hydrophilic CDH17-targeting antibody-drug conjugate exhibits anti-tumor efficacy in preclinical xenograft models