Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0NZTGT
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| ADC Name |
LBL-054
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| Synonyms |
LBL-054
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| Organization |
Nanjing Leadsbiolabs Co., Ltd.
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| Drug Status |
Investigative
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| Antibody Name |
humanized CDH17 IgG1 monoclonal antibody
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Antibody Info | ||||
| Antigen Name |
Cadherin-17 (CDH17)
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Antigen Info | ||||
| Payload Name |
Undisclosed
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| Therapeutic Target |
Stimulator of interferon genes protein (STING1)
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Target Info | ||||
| Linker Name |
Undisclosed
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ADC-specific functional property(2027 Update)
Bystander Killing Effect
| Bystander Killing Effect | Description | Reference |
|---|---|---|
| yes |
LBL-054 exhibited stronger bystander effect than LBL-054-Dxd conjugate.
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[1]
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References