Antibody-drug Conjugate Information
General Information of This Antibody-drug Conjugate (ADC)
| ADC ID |
DRG0MEYSI
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| ADC Name |
Anti-HER2 DVD-IgG1-h38c2-K99C TAMTA 1
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| Synonyms |
Anti-HER2 DVD-IgG1-H38c2-K99C-TAMTA 1
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| Drug Status |
Investigative
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| Drug-to-Antibody Ratio |
0.9
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| Structure |
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| Antibody Name |
Anti-HER2 DVD-IgG1-H38c2-K99C
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Antibody Info | ||||
| Antigen Name |
Receptor tyrosine-protein kinase erbB-2 (ERBB2)
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Antigen Info | ||||
| Payload Name |
5(6)-Carboxytetramethylrhodamine
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Payload Info | ||||
| Linker Name |
Mal-PEG3
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Linker Info | ||||
| Conjugate Type |
Maleimide can react with both uniquely reactive lysine and cysteine residues in the deep pocket of h38C2, Michael addition reaction.
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| Combination Type |
Maleimide-PEG3-5(6)-TAMRA
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